A Fixed Human Site Shared with Archaic Hominins
The seed paper reports a fixed human missense change, p.Asn1538Asp at chr12:21801082 in SUR2B, shared with Neanderthals and Denisovans. The node states precisely what was observed, separately from what it is worth, so the next node can do the interpretive work cleanly.
Questions this Concept answers
- Why does a site being fixed in modern humans and shared with Neanderthals and Denisovans constrain how old the change is?
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The seed paper reports a fixed human missense change, p.Asn1538Asp at chr12:21801082 in SUR2B, shared with Neanderthals and Denisovans. The node states precisely what was observed, separately from what it is worth, so the next node can do the interpretive work cleanly.
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