Dr Germán Rosas-Acosta
Apoptosis
Apoptosis is a genetically programmed, energy-dependent mechanism of cellular dismantling characterized by specific morphological and biochemical alterations that eliminate superfluous or damaged cells without inducing inflammation. The process is defined by the intrinsic and extrinsic signaling pathways that converge on the activation of cysteine-dependent aspartate-directed proteases, commonly known as caspases, leading to systematic protein degradation and nuclear condensation. This phenomenon represents a fundamental regulatory subfield within cellular biology that maintains tissue homeostasis and integrity by strictly controlling cell numbers and quality.