Bisulfite Sequencing and Methylation Arrays for CpG Methylation

The methylation assay layer; feeds methylation QTLs and epigenome annotation.

Questions this Concept answers

Why does a methylation array or bisulfite sequencing report a "beta value" between 0 and 1 rather than a simple present/absent call?

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Bisulfite Conversion for DNA Methylation Profiling in Epigenetics

Bisulfite conversion is an epigenetics technique that exploits a chemical difference between methylated and unmethylated cytosines to make DNA methylation detectable by sequencing: bisulfite selectiv…