Chromatin Remodeling

How histone modifications and ATP-dependent complexes control DNA accessibility for transcription.

Questions this Concept answers

Why does moving a nucleosome away from a DNA sequence change whether that sequence functions as a regulatory element?

jeremy Video

ATP-Dependent Nucleosome Remodeling Complexes in Molecular Biology

Nucleosome remodeling complexes are ATP-hydrolyzing molecular machines that alter chromatin architecture in space and time, making DNA wrapped around histone octamers accessible (or inaccessible) to …