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Clinical Signs of Median Nerve Injury in Anatomy

Median nerve injury produces characteristic motor deficits determined by the level of injury: proximal injury (e.g., at the supracondylar region) impairs finger flexion via forearm flexor muscles, producing the "pointing index" sign in children and the "hand of benediction" in adults, while distal injury (at or below the carpal tunnel) spares finger flexion but impairs thenar muscle function, specifically thumb abduction. This concept belongs to clinical anatomy/neuroanatomy, relating peripheral nerve lesion localization to the muscles the median nerve innervates and to the resulting clinical sign, in relation to the broader discipline of peripheral nerve injury diagnosis.