Enzyme-Substrate Complex
Substrate binds reversibly in the active site to form ES, whose formation saturates as substrate rises; catalysis proceeds from ES rather than from free substrate, which is why enzyme rate is hyperbolic in [S] rather than first order.
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Substrate binds reversibly in the active site to form ES, whose formation saturates as substrate rises; catalysis proceeds from ES rather than from free substrate, which is why enzyme rate is hyperbolic in [S] rather than first order.
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