Expression Quantitative Trait Loci: Mapping Variants to Expression Levels

The most direct statistical evidence that a variant affects a gene. Spine node.

Questions this Concept answers

Why is an eQTL considered more direct evidence that a variant affects a gene than a GWAS disease hit alone?

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cis and trans eQTL Analysis Using Linear Regression

Expression quantitative trait locus (eQTL) analysis tests, for each genotype–gene pair, whether the number of copies of a minor allele an individual carries is linearly associated with that gene's ex…