GC Clamp
One or two G or C bases in the last five 3' positions strengthen terminal binding so the polymerase starts from a firmly anchored end. More than three GC in that window over-stabilizes the terminus and promotes extension from partial matches.
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One or two G or C bases in the last five 3' positions strengthen terminal binding so the polymerase starts from a firmly anchored end. More than three GC in that window over-stabilizes the terminus and promotes extension from partial matches.
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