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Hill Equation

For cooperative multi-subunit enzymes, v = Vmax[S]^n/(K0.5^n + [S]^n) gives a sigmoidal curve; the Hill coefficient n exceeding 1 signals positive cooperativity and is an empirical index, always at most the number of binding sites.

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For cooperative multi-subunit enzymes, v = Vmax[S]^n/(K0.5^n + [S]^n) gives a sigmoidal curve; the Hill coefficient n exceeding 1 signals positive cooperativity and is an empirical index, always at most the number of binding sites.

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