This concept covers the interpretation of hepatitis B serologic markers within hepatology, grounded in the broader principle of classifying liver injury by pattern (hepatocellular vs. cholestatic) before identifying underlying cause. It defines the distinct antigen and antibody markers of hepatitis B infection (surface antigen, surface antibody, core IgM and IgG antibodies, e antigen) and how their combinations correspond to defined disease states—acute infection, chronic infection, resolved infection with immunity, vaccination, and susceptibility—based on the natural history and immunologic progression of hepatitis B virus infection.
This concept covers the interpretation of hepatitis B serologic markers within hepatology, grounded in the broader principle of classifying liver injury by pattern (hepatocellular vs. cholestatic) be…