LD Score Regression for SNP Heritability and Confounding

Standard diagnostic and the base for stratified LDSC, which finds the cell type.

Questions this Concept answers

Why does the slope of the LD score regression relate to polygenic signal rather than confounding?

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Estimating SNP Heritability with LD Score Regression in Statistical Genetics

LD score regression is a statistical genetics method for estimating SNP heritability (and related quantities) from GWAS summary statistics alone, addressing two core complications: linkage disequilib…