Linking Peaks to Genes by Co-Variation across Single Cells

The computational core of sketch 4; apply and analyze questions about correlation pitfalls.

Questions this Concept answers

Why can co-variation between a peak and a gene across single cells arise even without a direct regulatory effect?

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Calling snATAC-Seq Peaks with MACS2 and Linking Peaks to Genes

This concept covers peak calling and peak-to-gene linkage in single-cell chromatin accessibility (snATAC-seq) analysis: identifying high-confidence genomic regions of open chromatin (peaks) and stati…