Lithium, TCA and Antipsychotic Toxicity Emergencies
This covers four psychiatric emergencies in pharmacology/psychiatry: antipsychotic-induced extrapyramidal symptoms (with acute dystonia as the emergent form), lithium toxicity, tricyclic antidepressant (TCA) toxicity, and suicidal ideation. Each is defined by a receptor- or channel-level mechanism of drug action (D2 dopamine receptor blockade, lithium's effects on thyroid/renal/cardiac tissue, TCA blockade of GABA-A, muscarinic, alpha-1, and cardiac sodium channels), a characteristic symptom timeline and presentation, and a mechanism-directed treatment or intervention rule. As a subset of psychopharmacology, these concepts link drug receptor pharmacology to acute clinical risk, requiring recognition of onset timing and directed antidotal or supportive management to prevent harm.
Lithium, TCA and Antipsychotic Toxicity Emergencies
This covers four psychiatric emergencies in pharmacology/psychiatry: antipsychotic-induced extrapyramidal symptoms (with acute dystonia as the emergent form), lithium toxicity, tricyclic antidepressa…