Michaelis Constant
Km = (k-1 + kcat)/k1 is the substrate concentration giving half-maximal rate; it equals the true dissociation constant Ks only when kcat << k-1, so Km is an apparent affinity, not a binding constant.
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Km = (k-1 + kcat)/k1 is the substrate concentration giving half-maximal rate; it equals the true dissociation constant Ks only when kcat << k-1, so Km is an apparent affinity, not a binding constant.
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