Conceptual

NCLEX RN Review: Cholinergic (PNS) and Anticholinergic (SNS) Drugs

The core principle governing this domain is the antagonistic regulation within the Autonomic Nervous System (ANS), specifically delineating the functional opposition between Sympathetic (adrenergic) and Parasympathetic (cholinergic/colonic) divisions. The theoretical framework defines cholinergic agents as parasympathomimetics that mimic acetylcholine neurotransmission, while anticholinergic agents act by competitively blocking muscarinic receptors to inhibit colonic effects; their therapeutic application depends on modulating the physiological balance between "rest and digest" versus "fight or flight" states.