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Nonlinear Regression of Kinetic Data

Km and Vmax are now fit directly to the untransformed hyperbola by weighted least squares, which respects the real error structure of the rate measurements; reciprocal plots distort those errors and are retained only for visual diagnosis of inhibition patterns.

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Km and Vmax are now fit directly to the untransformed hyperbola by weighted least squares, which respects the real error structure of the rate measurements; reciprocal plots distort those errors and are retained only for visual diagnosis of inhibition patterns.

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