Obstructive Sleep Apnea as a Cause of Secondary Hypertension in Cardiovascular Pathology
This concept covers obstructive sleep apnea (OSA) as a mechanism of secondary hypertension within cardiovascular pathology, in which upper airway obstruction during sleep (from redundant pharyngeal/soft tissue) causes recurrent pauses in effective ventilation. The resulting failure to adequately exhale carbon dioxide leads to CO2 retention, which, via the carbonic anhydrase-mediated equilibrium, produces a respiratory acidosis; chronic OSA is further linked to development of secondary hypertension. This situates OSA within the broader relationship between respiratory pathophysiology (ventilation, acid-base balance) and cardiovascular disease (secondary hypertension).
Obstructive Sleep Apnea as a Cause of Secondary Hypertension in Cardiovascular Pathology
This concept covers obstructive sleep apnea (OSA) as a mechanism of secondary hypertension within cardiovascular pathology, in which upper airway obstruction during sleep (from redundant pharyngeal/s…