Phase Problem
Detectors record intensities, so the phase of every structure factor is lost, yet the phases dominate the appearance of the reconstructed density. No amount of better data recovers them; phases must be supplied from a model, from heavy-atom differences, or from anomalous scattering.
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Detectors record intensities, so the phase of every structure factor is lost, yet the phases dominate the appearance of the reconstructed density. No amount of better data recovers them; phases must be supplied from a model, from heavy-atom differences, or from anomalous scattering.
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