A diagnostic-imaging approach in which the degree of polarization and diffuse intensity of broadband terahertz light, altered by Mie scattering from micron-scale tissue structures, reveal structural changes associated with disease such as tumor budding or burn boundaries. A Monte Carlo model of polarized-light transport through highly attenuating tissue predicts scatterer-size-dependent contrast in the Stokes vectors and in the Lu-Chipman-decomposed Mueller matrix; the predictions are validated against polypropylene-in-gelatin phantoms and an ex vivo porcine burn injury.
A study showing that polarization-sensitive terahertz imaging can reveal structural (Mie-scattering) changes in biological tissue. The authors build a Monte Carlo simulation of broadband, off-specula…