Promoter Capture Hi-C and HiChIP for Enhancer-Promoter Links

The targeted assays that actually deliver enhancer-to-gene links at usable resolution.

Questions this Concept answers

Why is HiChIP able to enrich specifically for contacts involving a factor like cohesin or an active mark?

jeremy Text

PLAC-Seq - Wikipedia

PLAC-seq (and the near-identical HiChIP) is a protein-centric 3C method: chromatin contacts are made by in situ proximity ligation inside intact nuclei first, then chromatin immunoprecipitation again…