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Psychiatric Emergencies Part 2 of 2 (Psychiatry) (Pharmacology) - USMLE Step 1

This covers four psychiatric emergencies in pharmacology/psychiatry: antipsychotic-induced extrapyramidal symptoms (with acute dystonia as the emergent form), lithium toxicity, tricyclic antidepressant (TCA) toxicity, and suicidal ideation. Each is defined by a receptor- or channel-level mechanism of drug action (D2 dopamine receptor blockade, lithium's effects on thyroid/renal/cardiac tissue, TCA blockade of GABA-A, muscarinic, alpha-1, and cardiac sodium channels), a characteristic symptom timeline and presentation, and a mechanism-directed treatment or intervention rule. As a subset of psychopharmacology, these concepts link drug receptor pharmacology to acute clinical risk, requiring recognition of onset timing and directed antidotal or supportive management to prevent harm.