Reading ABCC9's Constraint Numbers as a Single Argument
The capstone of this sub-domain. LOEUF 0.482, dN/dS 0.126 and CADD 19.01 for the fixed p.Asn1538Asp change are three separate measurements on three timescales, and the student assembles them into the one claim they jointly support — this gene has been held still — while ruling out the claim they do not support, that any of it explains a 2.1 Hz pitch difference between living people.
Questions this Concept answers
- Why are a within-species loss-of-function shortfall, a cross-species substitution ratio, and a per-site damage score treated as evidence on three different timescales?
This Concept is waiting for its first lesson!
The capstone of this sub-domain. LOEUF 0.482, dN/dS 0.126 and CADD 19.01 for the fixed p.Asn1538Asp change are three separate measurements on three timescales, and the student assembles them into the one claim they jointly support — this gene has been held still — while ruling out the claim they do not support, that any of it explains a 2.1 Hz pitch difference between living people.
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