Silencing an Enhancer with dCas9-KRAB CRISPR Interference
The decisive single-element experiment linking enhancer to gene in the endogenous context.
Questions this Concept answers
- Why is CRISPRi silencing of an enhancer considered stronger evidence than an MPRA for linking an enhancer to a gene in vivo?
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The decisive single-element experiment linking enhancer to gene in the endogenous context.
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