Statistical Fine-Mapping: Posterior Inclusion Probabilities and Credible Sets

Turns a locus into a ranked short list. The method output that all functional work consumes.

Questions this Concept answers

Why does fine-mapping report a posterior inclusion probability instead of a single answer for each variant?

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Statistical Fine-Mapping of Causal Variants in GWAS

Statistical fine-mapping is a Bayesian inference method used after genome-wide association studies (GWAS) to distinguish likely causal genetic variants from merely correlated ones within an associate…