Sum of Single Effects Fine-Mapping with Multiple Causal Variants

The current standard; explains why credible sets come in groups and how to read them.

Questions this Concept answers

Why does SuSiE fit multiple 'single-effect' components rather than one model with all variants together?

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Fine-Mapping Mendelian Randomization for Drug Target Discovery in Statistical Genetics

Mendelian randomization (MR) is a statistical genetics method that uses genetic variants as instrumental variables to estimate the causal effect of a modifiable exposure (e.g., a molecular trait such…