Vitamin D Hormonal Regulation of Immune Function
The core principle describes the endocrine mechanism by which vitamin D functions as a steroid hormone to modulate innate and adaptive immune responses. This theory operates within the domain of immunometabolism, specifically addressing the genomic regulation of immune cell differentiation, cytokine production, and antimicrobial peptide synthesis. The concept establishes that sufficient hormonal levels are required to maintain homeostatic balance between pro-inflammatory and anti-inflammatory pathways, thereby preventing excessive immune activation.
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The core principle describes the endocrine mechanism by which vitamin D functions as a steroid hormone to modulate innate and adaptive immune responses. This theory operates within the domain of immunometabolism, specifically addressing the genomic regulation of immune cell differentiation, cytokine production, and antimicrobial peptide synthesis. The concept establishes that sufficient hormonal levels are required to maintain homeostatic balance between pro-inflammatory and anti-inflammatory pathways, thereby preventing excessive immune activation.
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